BBH VanEck Biotech ETF

Expense Ratio
0.35%
Dividend
0.41%
Previous close
$232.34
Est. 12 months change
+9.08%
Projected Price
$253.44

Profitability Metrics

Return on Equity (ROE)
12.82%
Return on Assets (ROA)
4.12%
Return on Invested Capital (ROIC)
13.56%
Weighted Average Cost of Capital (WACC)
7.39%
ROIC - WACC
6.17%
Updated : 2026-09-08 17:51 ET

Valuation Metrics

P/E Ratio
29.85
Forward P/E
20.57
PEG Ratio
3.33
Debt Current Ratio
3.01

Growth & Cash Flow

Gross Margin
57.05%
Operating Margin
13.48%
FCF Margin
25.20%
TTM Revenue Growth
20.12%
Projected 12M EPS Growth
45.13%
The above metrics represent weighted averages, calculated using each stock's individual value weighted by its proportion of ETF holdings.

Top 10 Holdings

Stock TickerWeight
AMGN15.58%
GILD12.74%
VRTX8.59%
REGN6.85%
MRNA5.80%
NTRA5.02%
IQV5.01%
RVMD4.98%
ARGX4.76%
ILMN3.32%

ETF Analysis

Fund Overview

VanEck Biotech ETF (BBH) currently reports 25 stock positions (subject to change), placing it in the deliberately concentrated range by holdings breadth. The top line-up is AMGN (15.58%), GILD (12.74%), VRTX (8.59%), with AMGN as the largest single weight at 15.58%. Together, the top three holdings account for 36.91%, which points to a top-heavy structure where idiosyncratic risk in the largest holdings is a relevant consideration. This structure gives the portfolio a dual character: meaningful exposure to its highest-conviction names, alongside enough breadth to dampen idiosyncratic noise.

Profitability & Capital Efficiency

Examining the portfolio through a capital allocation lens, ROIC is 13.56%, WACC is 7.39%, and the economic spread is 6.17%. On balance, holdings are generating returns above their cost of capital, though the margin is slim enough to warrant attention. Supporting metrics show ROE at 12.82% and ROA at 4.12%, a combination that helps frame whether profitability strength is broad enough to hold through different market conditions. Taken together, the return profile suggests a portfolio that is value-creative but with less room for execution slippage.

Valuation

Valuation currently screens at trailing P/E of 29.85, forward P/E of 20.57, PEG of 3.33. Trailing and forward multiples are somewhat apart, indicating the market is pricing measured earnings growth without aggressive expansion assumptions. At this PEG level, the portfolio is priced generously relative to its expected earnings trajectory — execution risk is meaningfully priced in. The aggregate current ratio of 3.01 reflects a holding set with strong liquidity buffers against short-term stress. The valuation profile here is neither obviously cheap nor dramatically expensive — a setup where the return case is built more on earnings delivery than on re-rating potential.

Margins & Cash Generation

From gross to free cash flow, gross margin sits at 57.05%, operating margin at 13.48%, and free cash flow margin at 25.20%. At this gross margin level, the holdings demonstrate adequate production efficiency without commanding premium pricing. Operating margins are thin enough to warrant attention — businesses at this level are more exposed to cost inflation. At this level, FCF margins reflect a portfolio of businesses with genuine capital efficiency and strong cash-based earnings quality. The margin profile warrants careful consideration — businesses with compressed margins have less room to absorb cost pressure or revenue softness.

Growth & Forward Outlook

Revenue momentum and analyst targets together paint a picture where the estimated 12-month price change of 9.17%, where target-based return potential appears limited without multiple expansion, while TTM revenue growth of 20.12% reflecting top-line acceleration that, if sustained, supports the forward earnings case. Reported revenue growth is the operational foundation; the analyst target spread shows what the market is willing to pay above it — and that premium can evaporate quickly if delivery slips. For investors, the central question is whether the operating momentum visible in revenues is durable enough to support the price appreciation implied by consensus targets. The estimated 12-month price change is a weighted composite of analyst price target estimates adjusted by each holding's ETF weight, sourced from publicly available data, and should not be interpreted as a reliable prediction of future performance.

Conclusion

Buy

The fundamental case holds up across most key dimensions — the combination of positive economic spread, reasonable valuation, and analyst support is constructive.

These findings are based solely on the metrics presented and do not constitute an investment recommendation. Always perform your own due diligence before committing capital.