XPH State Street SPDR S&P Pharmaceuticals ETF

Expense Ratio
0.35%
Dividend
0.68%
Previous close
$54.72
Est. 12 months change
+61.50%
Projected Price
$88.37

Profitability Metrics

Return on Equity (ROE)
-16.93%
Return on Assets (ROA)
-6.43%
Return on Invested Capital (ROIC)
-9.88%
Weighted Average Cost of Capital (WACC)
7.58%
ROIC - WACC
-17.45%
Updated : 2026-04-04 06:37 ET

Valuation Metrics

P/E Ratio
9.33
Forward P/E
9.41
PEG Ratio
1.39
Debt Current Ratio
8.34

Growth & Cash Flow

Gross Margin
66.30%
Operating Margin
-40.08%
FCF Margin
28.94%
TTM Revenue Growth
44.92%
Projected 12M EPS Growth
-0.78%

Price Change

Price % from 50 SMA
-1.64%
Price % from 200 SMA
8.83%
6 Months
13.36%
1 Year
29.67%
2 Years
30.29%
The above metrics represent weighted averages, calculated using each stock's individual value weighted by its proportion of ETF holdings.

Top 10 Holdings

Stock TickerWeight
CORT2.36%
ELVN2.33%
TERN2.14%
PRGO2.12%
DFTX2.09%
MBX2.08%
AXSM2.04%
EWTX2.03%
INVA1.98%
PFE1.98%

ETF Analysis

Fund Overview

State Street SPDR S&P Pharmaceuticals ETF (XPH) currently reports 59 stock positions (subject to change), placing it in the moderately diversified range by holdings breadth. The top line-up is CORT (2.36%), ELVN (2.33%), TERN (2.14%), with CORT as the largest single weight at 2.36%. Together, the top three holdings account for 6.83%, which indicates that performance drivers are distributed more evenly across the broader basket. This architecture allows the fund to express a clear investment thesis at the top while relying on the broader basket to manage idiosyncratic volatility.

Profitability & Capital Efficiency

From a capital efficiency perspective, ROIC is -9.88%, WACC is 7.58%, and the economic spread is -17.45%. On balance, holdings are currently generating returns below their cost of capital, which may weigh on intrinsic value over time. Supporting metrics show ROE at -16.93% and ROA at -6.43%, a combination that helps frame whether profitability strength is broad enough to hold through different market conditions. Taken together, the return profile suggests a portfolio that likely needs operating improvement before returns quality can be considered durable.

Valuation

Valuation currently screens at trailing P/E of 9.33, forward P/E of 9.41, PEG of 1.39. Trailing and forward P/E are close together, implying the market does not expect a significant change in the earnings trajectory over the near term. A PEG below 1.5 implies the portfolio's growth rate is not fully reflected in the current multiple — a constructive signal for growth-adjusted value. The current ratio of 8.34 indicates holdings are well-positioned to meet near-term obligations. The valuation profile here is neither obviously cheap nor dramatically expensive — a setup where the return case is built more on earnings delivery than on re-rating potential.

Margins & Cash Generation

On the margin front: gross margin sits at 66.30%, operating margin at -40.08%, and free cash flow margin at 28.94%. At this gross margin level, the portfolio's holdings demonstrate significant pricing power and production efficiency. The operating margin reading is weak, suggesting cost structures are outpacing revenue generation across much of the portfolio. At this FCF margin level, the underlying holdings have considerable financial flexibility without reliance on external financing. The margin stack is not uniformly strong, which means the portfolio's earnings resilience under adverse conditions is less certain.

Growth & Forward Outlook

On the forward picture: TTM revenue growth of 44.92% reflecting robust top-line expansion across the underlying holdings. Consensus EPS estimates point to a decline of -0.8% over the next 12 months, adding a layer of risk to the forward case and warranting caution on the earnings trajectory. Analyst price targets suggest street expectations point to meaningful upside if execution holds on a 12-month view. Revenue growth is grounded in reported results; price targets are forward projections that embed assumptions about multiple expansion, earnings delivery, and macro conditions. The key risk in both directions is whether the underlying businesses can maintain their operating trajectory as macro and sector conditions evolve. The estimated 12-month price change is a weighted composite of analyst price target estimates adjusted by each holding's ETF weight, sourced from publicly available data, and should not be interpreted as a reliable prediction of future performance.

Conclusion

Buy

The composite picture leans positive, with capital efficiency and growth momentum providing the core of the investment thesis.

These findings are based solely on the metrics presented and do not constitute an investment recommendation. Always perform your own due diligence before committing capital.